This paper describes a guidance system for blind and partially sighted people with the aim of coping in the known and unknown internal and external spaces without the assistance of human guides. This work represents a significant step forward in the application of innovative technological solutions to increase independence and improve the quality of life for people with disabilities. This paper describes the technical and functional architecture of the system for orientation and guidance of a blind person using available modern technology. The described system consists of a digital sensor for determining the location by dead reckoning technique, infrared marks in space and handheld device that provides voice guidance instructions.